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Effects of miR‐145‐5p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways
We aimed to detect the effects of miR‐145‐5p on the cell proliferation, apoptosis, migration, and invasion in NRAS‐mutant, BRAF‐mutant, and wild‐type melanoma cells, in order to figure out the potential mechanisms and provide a novel therapeutic target of melanoma. RT‐qPCR and western blot were used...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387172/ https://www.ncbi.nlm.nih.gov/pubmed/28332309 http://dx.doi.org/10.1002/cam4.1030 |