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Telocytes: a potential defender in the spleen of Npc1 mutant mice

Niemann–Pick disease, type C1 (Npc1), is an atypical lysosomal storage disorder caused by autosomal recessive inheritance of mutations in Npc1 gene. In the Npc1 mutant mice (Npc1(−/−)), the initial manifestation is enlarged spleen, concomitant with free cholesterol accumulation. Telocytes (TCs), a n...

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Detalles Bibliográficos
Autores principales: Zhang, Bichao, Yang, Ciqing, Qiao, Liang, Li, Qiuling, Wang, Congrui, Yan, Xin, Lin, Juntang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387173/
https://www.ncbi.nlm.nih.gov/pubmed/27860245
http://dx.doi.org/10.1111/jcmm.13024