Vps33b is crucial for structural and functional hepatocyte polarity

BACKGROUND & AIMS: In the normal liver, hepatocytes form a uniquely polarised cell layer that enables movement of solutes from sinusoidal blood to canalicular bile. Whilst several cholestatic liver diseases with defects of hepatocyte polarity have been identified, the molecular mechanisms of pat...

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Detalles Bibliográficos
Autores principales: Hanley, Joanna, Dhar, Dipok Kumar, Mazzacuva, Francesca, Fiadeiro, Rebeca, Burden, Jemima J., Lyne, Anne-Marie, Smith, Holly, Straatman-Iwanowska, Anna, Banushi, Blerida, Virasami, Alex, Mills, Kevin, Lemaigre, Frédéric P., Knisely, A.S., Howe, Steven, Sebire, Neil, Waddington, Simon N., Paulusma, Coen C., Clayton, Peter, Gissen, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387182/
https://www.ncbi.nlm.nih.gov/pubmed/28082148
http://dx.doi.org/10.1016/j.jhep.2017.01.001

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