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Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice

BACKGROUND: Eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, C20:4n-6) are long-chain polyunsaturated fatty acids (LCPUFAs) with relevant roles in the organism. EPA and DHA are synthesized from the precursor alpha-linolenic acid (ALA, C18:3n-3), w...

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Detalles Bibliográficos
Autores principales: Valenzuela, Rodrigo, Echeverria, Francisca, Ortiz, Macarena, Rincón-Cervera, Miguel Ángel, Espinosa, Alejandra, Hernandez-Rodas, María Catalina, Illesca, Paola, Valenzuela, Alfonso, Videla, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387240/
https://www.ncbi.nlm.nih.gov/pubmed/28395666
http://dx.doi.org/10.1186/s12944-017-0450-5