Cargando…
Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin
VanA-type resistance to glycopeptide antibiotics in clinical enterococci is regulated by the VanS(A)R(A) two-component signal transduction system. The nature of the molecular ligand that is recognised by the VanS(A) sensory component has not hitherto been identified. Here we employ purified, intact...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387412/ https://www.ncbi.nlm.nih.gov/pubmed/28397853 http://dx.doi.org/10.1038/srep46180 |