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Hepatocytic parental progenitor cells of rat small hepatocytes maintain self-renewal capability after long-term culture
The liver has a variety of functions for maintaining homeostasis, and hepatocytes play a major role. In contrast with the high regenerative capacity of mature hepatocytes (MHs) in vivo, they have not been successfully expanded ex vivo. Here we demonstrate that CD44-positive cells sorted from small h...
Autores principales: | Ishii, Masayuki, Kino, Junichi, Ichinohe, Norihisa, Tanimizu, Naoki, Ninomiya, Takafumi, Suzuki, Hiromu, Mizuguchi, Toru, Hirata, Koichi, Mitaka, Toshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387414/ https://www.ncbi.nlm.nih.gov/pubmed/28397810 http://dx.doi.org/10.1038/srep46177 |
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