Cargando…

Enantioselective Synthesis of (−)-Acetylapoaranotin

[Image: see text] The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (−)-acetylapoaranotin (3) is reported. The concise synthesis was enabled by an eight-step synthesis of a key cyclohexadienol-containing amino ester building block. The absolute stere...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Haoxuan, Regan, Clinton J., Codelli, Julian A., Romanato, Paola, Puchlopek-Dermenci, Angela L. A., Reisman, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387676/
https://www.ncbi.nlm.nih.gov/pubmed/28349698
http://dx.doi.org/10.1021/acs.orglett.7b00418