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An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein

Recently, progress has been made in the development of vaccines and monoclonal antibody cocktails that target the Ebola coat glycoprotein (GP). Based on the mutation rates for Ebola virus given its natural sequence evolution, these treatment strategies are likely to impose additional selection press...

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Detalles Bibliográficos
Autores principales: Quinlan, Devin S., Raman, Rahul, Tharakaraman, Kannan, Subramanian, Vidya, del Hierro, Gabriella, Sasisekharan, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387726/
https://www.ncbi.nlm.nih.gov/pubmed/28397835
http://dx.doi.org/10.1038/srep45886