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An inter-residue network model to identify mutational-constrained regions on the Ebola coat glycoprotein
Recently, progress has been made in the development of vaccines and monoclonal antibody cocktails that target the Ebola coat glycoprotein (GP). Based on the mutation rates for Ebola virus given its natural sequence evolution, these treatment strategies are likely to impose additional selection press...
Autores principales: | Quinlan, Devin S., Raman, Rahul, Tharakaraman, Kannan, Subramanian, Vidya, del Hierro, Gabriella, Sasisekharan, Ram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387726/ https://www.ncbi.nlm.nih.gov/pubmed/28397835 http://dx.doi.org/10.1038/srep45886 |
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