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Colorectal Cancer in Jordan: Survival Rate and Its Related Factors

Objectives. To estimate the survival rate of colorectal cancer (CRC) and determine its predictors among Jordanian patients who were diagnosed in the period of 2005–2010. Methods. This study was based on Jordan cancer registry. All CRC cases that were registered in cancer registry during 2005–2010 we...

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Autores principales: Sharkas, Ghazi Faisal, Arqoub, Kamal H., Khader, Yousef S., Tarawneh, Mohammad R., Nimri, Omar F., Al-zaghal, Marwan J., Subih, Hadil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387838/
https://www.ncbi.nlm.nih.gov/pubmed/28458690
http://dx.doi.org/10.1155/2017/3180762
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author Sharkas, Ghazi Faisal
Arqoub, Kamal H.
Khader, Yousef S.
Tarawneh, Mohammad R.
Nimri, Omar F.
Al-zaghal, Marwan J.
Subih, Hadil S.
author_facet Sharkas, Ghazi Faisal
Arqoub, Kamal H.
Khader, Yousef S.
Tarawneh, Mohammad R.
Nimri, Omar F.
Al-zaghal, Marwan J.
Subih, Hadil S.
author_sort Sharkas, Ghazi Faisal
collection PubMed
description Objectives. To estimate the survival rate of colorectal cancer (CRC) and determine its predictors among Jordanian patients who were diagnosed in the period of 2005–2010. Methods. This study was based on Jordan cancer registry. All CRC cases that were registered in cancer registry during 2005–2010 were analyzed using the survival analysis. The last date for follow-up was 1st Oct 2016. Results. A total of 3005 patients with CRC were registered during 2005–2010. The overall 5-year and 10-year survival rates for patients with CRC were 58.2% and 51.8%, respectively. The 5-year survival rate decreased significantly from 60.4% for the age <50 years to 49.3% for the age ≥70 years (p < 0.005). The 5-year survival rate was 72.1% for the localized stage, 53.8% for the regional stage, and 22.6% for the distant metastasis. In the multivariate analysis, the only factors that were significantly associated with survival were age, grade, stage, and location of tumor. Conclusions. The overall 5-year and ten-year survival rates for CRC were 58.2% and 51.8%, respectively. Increased age, poor differentiation, advanced cancer stage, and right-sided cancers were associated with lower survival rates. Screening strategies are needed for early detection of colon adenomas and colorectal cancer in Jordan.
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spelling pubmed-53878382017-04-30 Colorectal Cancer in Jordan: Survival Rate and Its Related Factors Sharkas, Ghazi Faisal Arqoub, Kamal H. Khader, Yousef S. Tarawneh, Mohammad R. Nimri, Omar F. Al-zaghal, Marwan J. Subih, Hadil S. J Oncol Research Article Objectives. To estimate the survival rate of colorectal cancer (CRC) and determine its predictors among Jordanian patients who were diagnosed in the period of 2005–2010. Methods. This study was based on Jordan cancer registry. All CRC cases that were registered in cancer registry during 2005–2010 were analyzed using the survival analysis. The last date for follow-up was 1st Oct 2016. Results. A total of 3005 patients with CRC were registered during 2005–2010. The overall 5-year and 10-year survival rates for patients with CRC were 58.2% and 51.8%, respectively. The 5-year survival rate decreased significantly from 60.4% for the age <50 years to 49.3% for the age ≥70 years (p < 0.005). The 5-year survival rate was 72.1% for the localized stage, 53.8% for the regional stage, and 22.6% for the distant metastasis. In the multivariate analysis, the only factors that were significantly associated with survival were age, grade, stage, and location of tumor. Conclusions. The overall 5-year and ten-year survival rates for CRC were 58.2% and 51.8%, respectively. Increased age, poor differentiation, advanced cancer stage, and right-sided cancers were associated with lower survival rates. Screening strategies are needed for early detection of colon adenomas and colorectal cancer in Jordan. Hindawi 2017 2017-03-28 /pmc/articles/PMC5387838/ /pubmed/28458690 http://dx.doi.org/10.1155/2017/3180762 Text en Copyright © 2017 Ghazi Faisal Sharkas et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Sharkas, Ghazi Faisal
Arqoub, Kamal H.
Khader, Yousef S.
Tarawneh, Mohammad R.
Nimri, Omar F.
Al-zaghal, Marwan J.
Subih, Hadil S.
Colorectal Cancer in Jordan: Survival Rate and Its Related Factors
title Colorectal Cancer in Jordan: Survival Rate and Its Related Factors
title_full Colorectal Cancer in Jordan: Survival Rate and Its Related Factors
title_fullStr Colorectal Cancer in Jordan: Survival Rate and Its Related Factors
title_full_unstemmed Colorectal Cancer in Jordan: Survival Rate and Its Related Factors
title_short Colorectal Cancer in Jordan: Survival Rate and Its Related Factors
title_sort colorectal cancer in jordan: survival rate and its related factors
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387838/
https://www.ncbi.nlm.nih.gov/pubmed/28458690
http://dx.doi.org/10.1155/2017/3180762
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