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High-coverage methylation data of a gene model before and after DNA damage and homologous repair

Genome-wide methylation analysis is limited by its low coverage and the inability to detect single variants below 10%. Quantitative analysis provides accurate information on the extent of methylation of single CpG dinucleotide, but it does not measure the actual polymorphism of the methylation profi...

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Detalles Bibliográficos
Autores principales: Pezone, Antonio, Russo, Giusi, Tramontano, Alfonso, Florio, Ermanno, Scala, Giovanni, Landi, Rosaria, Zuchegna, Candida, Romano, Antonella, Chiariotti, Lorenzo, Muller, Mark T., Gottesman, Max E., Porcellini, Antonio, Avvedimento, Enrico V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387920/
https://www.ncbi.nlm.nih.gov/pubmed/28398335
http://dx.doi.org/10.1038/sdata.2017.43