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High-coverage methylation data of a gene model before and after DNA damage and homologous repair
Genome-wide methylation analysis is limited by its low coverage and the inability to detect single variants below 10%. Quantitative analysis provides accurate information on the extent of methylation of single CpG dinucleotide, but it does not measure the actual polymorphism of the methylation profi...
Autores principales: | Pezone, Antonio, Russo, Giusi, Tramontano, Alfonso, Florio, Ermanno, Scala, Giovanni, Landi, Rosaria, Zuchegna, Candida, Romano, Antonella, Chiariotti, Lorenzo, Muller, Mark T., Gottesman, Max E., Porcellini, Antonio, Avvedimento, Enrico V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387920/ https://www.ncbi.nlm.nih.gov/pubmed/28398335 http://dx.doi.org/10.1038/sdata.2017.43 |
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