Predictive prognostic value of neutrophil–lymphocytes ratio in acute coronary syndrome

OBJECTIVE: To assess the relationship between neutrophil–lymphocytes ratio (NLR) at admission and patient outcome over a period of six month in subjects with acute coronary syndrome (ACS). METHODS: A total of 435 consecutive patients presenting with ACS were enrolled and 400 patients completed the study. Patients were categorized into 2 groups: the NLR group 1 (NLR ≤ 5.25; n = 265, 66.25%) and the NLR group 2 (NLR > 5.25; n = 135, 33.75%). The primary outcomes were in-hospital and 6 months mortality. RESULTS: Forty-seven (11.8%) patients died during 6 months follow up. Higher mortality was seen in NLR group 2 (42/135, 34.1%) compared to NLR group 1 (5/265, 1.9%) with p value <0.001. CONCLUSION: Our study suggest that elevated NLR (>5.25) is independently associated with higher all-cause mortality rate up to 6 months period irrespective of ACS type.