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M. tuberculosis Secretory Protein ESAT-6 Induces Metabolic Flux Perturbations to Drive Foamy Macrophage Differentiation

The Foamy Macrophage (FM) differentiation forms a major component of the host dependent survival axis of M. tuberculosis. The FM which are characterized by the intracellular accumulation of lipid bodies (LBs), ensure a privileged existence for the bacilli through ready provision of nutrients and by...

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Detalles Bibliográficos
Autores principales:	Singh, Varshneya, Kaur, Charanpreet, Chaudhary, Vijay K., Rao, Kanury V. S, Chatterjee, Samrat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388048/ https://www.ncbi.nlm.nih.gov/pubmed/26250836 http://dx.doi.org/10.1038/srep12906

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