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Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review

In recent years, several drugs have been developed deriving from traditional products and current drug research is actively investigating the possible therapeutic roles of many Ayruvedic and Traditional Indian medicinal therapies. Among those being investigated is Turmeric. Its most important active...

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Detalles Bibliográficos
Autores principales: Amalraj, Augustine, Pius, Anitha, Gopi, Sreerag, Gopi, Sreeraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388087/
https://www.ncbi.nlm.nih.gov/pubmed/28417091
http://dx.doi.org/10.1016/j.jtcme.2016.05.005
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author Amalraj, Augustine
Pius, Anitha
Gopi, Sreerag
Gopi, Sreeraj
author_facet Amalraj, Augustine
Pius, Anitha
Gopi, Sreerag
Gopi, Sreeraj
author_sort Amalraj, Augustine
collection PubMed
description In recent years, several drugs have been developed deriving from traditional products and current drug research is actively investigating the possible therapeutic roles of many Ayruvedic and Traditional Indian medicinal therapies. Among those being investigated is Turmeric. Its most important active ingredient is curcuminoids. Curcuminoids are phenolic compounds commonly used as a spice, pigment and additive also utilized as a therapeutic agent used in several foods. Comprehensive research over the last century has revealed several important functions of curcuminoids. Various preclinical cell culture and animals studies suggest that curcuminoids have extensive biological activity as an antioxidant, neuroprotective, antitumor, anti-inflammatory, anti-acidogenic, radioprotective and arthritis. Different clinical trials also suggest a potential therapeutic role for curcuminoids in numerous chronic diseases such as colon cancer, lung cancer, breast cancer, inflammatory bowel diseases. The aim of this review is to summarize the chemistry, analog, metal complex, formulations of curcuminoids and their biological activities.
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spelling pubmed-53880872017-04-17 Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review Amalraj, Augustine Pius, Anitha Gopi, Sreerag Gopi, Sreeraj J Tradit Complement Med Review Article In recent years, several drugs have been developed deriving from traditional products and current drug research is actively investigating the possible therapeutic roles of many Ayruvedic and Traditional Indian medicinal therapies. Among those being investigated is Turmeric. Its most important active ingredient is curcuminoids. Curcuminoids are phenolic compounds commonly used as a spice, pigment and additive also utilized as a therapeutic agent used in several foods. Comprehensive research over the last century has revealed several important functions of curcuminoids. Various preclinical cell culture and animals studies suggest that curcuminoids have extensive biological activity as an antioxidant, neuroprotective, antitumor, anti-inflammatory, anti-acidogenic, radioprotective and arthritis. Different clinical trials also suggest a potential therapeutic role for curcuminoids in numerous chronic diseases such as colon cancer, lung cancer, breast cancer, inflammatory bowel diseases. The aim of this review is to summarize the chemistry, analog, metal complex, formulations of curcuminoids and their biological activities. Elsevier 2016-06-15 /pmc/articles/PMC5388087/ /pubmed/28417091 http://dx.doi.org/10.1016/j.jtcme.2016.05.005 Text en Copyright © 2016, Center for Food and Biomolecules, National Taiwan University. Production and hosting by Elsevier Taiwan LLC. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Amalraj, Augustine
Pius, Anitha
Gopi, Sreerag
Gopi, Sreeraj
Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review
title Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review
title_full Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review
title_fullStr Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review
title_full_unstemmed Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review
title_short Biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – A review
title_sort biological activities of curcuminoids, other biomolecules from turmeric and their derivatives – a review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388087/
https://www.ncbi.nlm.nih.gov/pubmed/28417091
http://dx.doi.org/10.1016/j.jtcme.2016.05.005
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