Cargando…
An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva
Saliva contains important personal physiological information that is related to some diseases, and it is a valuable source of biochemical information that can be collected rapidly, frequently, and without stress. In this article, we reported a new and simple localized surface plasmon resonance (LSPR...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388169/ https://www.ncbi.nlm.nih.gov/pubmed/28336901 http://dx.doi.org/10.3390/nano7030067 |
_version_ | 1782521084973678592 |
---|---|
author | Luo, Chongdai Wang, Yangyang Li, Xuemeng Jiang, Xueqin Gao, Panpan Sun, Kang Zhou, Jianhua Zhang, Zhiguang Jiang, Qing |
author_facet | Luo, Chongdai Wang, Yangyang Li, Xuemeng Jiang, Xueqin Gao, Panpan Sun, Kang Zhou, Jianhua Zhang, Zhiguang Jiang, Qing |
author_sort | Luo, Chongdai |
collection | PubMed |
description | Saliva contains important personal physiological information that is related to some diseases, and it is a valuable source of biochemical information that can be collected rapidly, frequently, and without stress. In this article, we reported a new and simple localized surface plasmon resonance (LSPR) substrate composed of polyaniline (PANI)-gold hybrid nanostructures as an optical sensor for monitoring the pH of saliva samples. The overall appearance and topography of the substrates, the composition, and the wettability of the LSPR surfaces were characterized by optical and scanning electron microscope (SEM) images, infrared spectra, and contact angles measurement, respectively. The PANI-gold hybrid substrate readily responded to the pH. The response time was very short, which was 3.5 s when the pH switched from 2 to 7, and 4.5 s from 7 to 2. The changes of visible-near-infrared (NIR) spectra of this sensor upon varying pH in solution showed that—for the absorption at given wavelengths of 665 nm and 785 nm—the sensitivities were 0.0299 a.u./pH (a.u. = arbitrary unit) with a linear range of pH = 5–8 and 0.0234 a.u./pH with linear range of pH = 2–8, respectively. By using this new sensor, the pH of a real saliva sample was monitored and was consistent with the parallel measurements with a standard laboratory method. The results suggest that this novel LSPR sensor shows great potential in the field of mobile healthcare and home medical devices, and could also be modified by different sensitive materials to detect various molecules or ions in the future. |
format | Online Article Text |
id | pubmed-5388169 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53881692017-04-13 An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva Luo, Chongdai Wang, Yangyang Li, Xuemeng Jiang, Xueqin Gao, Panpan Sun, Kang Zhou, Jianhua Zhang, Zhiguang Jiang, Qing Nanomaterials (Basel) Article Saliva contains important personal physiological information that is related to some diseases, and it is a valuable source of biochemical information that can be collected rapidly, frequently, and without stress. In this article, we reported a new and simple localized surface plasmon resonance (LSPR) substrate composed of polyaniline (PANI)-gold hybrid nanostructures as an optical sensor for monitoring the pH of saliva samples. The overall appearance and topography of the substrates, the composition, and the wettability of the LSPR surfaces were characterized by optical and scanning electron microscope (SEM) images, infrared spectra, and contact angles measurement, respectively. The PANI-gold hybrid substrate readily responded to the pH. The response time was very short, which was 3.5 s when the pH switched from 2 to 7, and 4.5 s from 7 to 2. The changes of visible-near-infrared (NIR) spectra of this sensor upon varying pH in solution showed that—for the absorption at given wavelengths of 665 nm and 785 nm—the sensitivities were 0.0299 a.u./pH (a.u. = arbitrary unit) with a linear range of pH = 5–8 and 0.0234 a.u./pH with linear range of pH = 2–8, respectively. By using this new sensor, the pH of a real saliva sample was monitored and was consistent with the parallel measurements with a standard laboratory method. The results suggest that this novel LSPR sensor shows great potential in the field of mobile healthcare and home medical devices, and could also be modified by different sensitive materials to detect various molecules or ions in the future. MDPI 2017-03-17 /pmc/articles/PMC5388169/ /pubmed/28336901 http://dx.doi.org/10.3390/nano7030067 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Luo, Chongdai Wang, Yangyang Li, Xuemeng Jiang, Xueqin Gao, Panpan Sun, Kang Zhou, Jianhua Zhang, Zhiguang Jiang, Qing An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
title | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
title_full | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
title_fullStr | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
title_full_unstemmed | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
title_short | An Optical Sensor with Polyaniline-Gold Hybrid Nanostructures for Monitoring pH in Saliva |
title_sort | optical sensor with polyaniline-gold hybrid nanostructures for monitoring ph in saliva |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388169/ https://www.ncbi.nlm.nih.gov/pubmed/28336901 http://dx.doi.org/10.3390/nano7030067 |
work_keys_str_mv | AT luochongdai anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT wangyangyang anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT lixuemeng anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT jiangxueqin anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT gaopanpan anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT sunkang anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT zhoujianhua anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT zhangzhiguang anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT jiangqing anopticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT luochongdai opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT wangyangyang opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT lixuemeng opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT jiangxueqin opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT gaopanpan opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT sunkang opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT zhoujianhua opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT zhangzhiguang opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva AT jiangqing opticalsensorwithpolyanilinegoldhybridnanostructuresformonitoringphinsaliva |