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Viral and Cellular mRNA Translation in Coronavirus-Infected Cells

Coronaviruses have large positive-strand RNA genomes that are 5′ capped and 3′ polyadenylated. The 5′-terminal two-thirds of the genome contain two open reading frames (ORFs), 1a and 1b, that together make up the viral replicase gene and encode two large polyproteins that are processed by viral prot...

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Detalles Bibliográficos
Autores principales: Nakagawa, K., Lokugamage, K.G., Makino, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388242/
https://www.ncbi.nlm.nih.gov/pubmed/27712623
http://dx.doi.org/10.1016/bs.aivir.2016.08.001