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Kynurenine Pathway Activation in Human African Trypanosomiasis

BACKGROUND. The kynurenine pathway of tryptophan oxidation is associated with central nervous system (CNS) inflammatory pathways. Inhibition of this pathway ameliorates CNS inflammation in rodent models of the late (meningoencephalitic) stage of human African trypanosomiasis (HAT). In this study, we...

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Detalles Bibliográficos
Autores principales:	Sternberg, Jeremy M., Forrest, Caroline M., Dalton, R. Neil, Turner, Charles, Rodgers, Jean, Stone, Trevor W., Kennedy, Peter G. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388295/ https://www.ncbi.nlm.nih.gov/pubmed/28013248 http://dx.doi.org/10.1093/infdis/jiw623

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