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Synergistic Interaction Between Phage Therapy and Antibiotics Clears Pseudomonas Aeruginosa Infection in Endocarditis and Reduces Virulence

BACKGROUND. Increasing antibiotic resistance warrants therapeutic alternatives. Here we investigated the efficacy of bacteriophage-therapy (phage) alone or combined with antibiotics against experimental endocarditis (EE) due to Pseudomonas aeruginosa, an archetype of difficult-to-treat infection. ME...

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Detalles Bibliográficos
Autores principales:	Oechslin, Frank, Piccardi, Philippe, Mancini, Stefano, Gabard, Jérôme, Moreillon, Philippe, Entenza, José M., Resch, Gregory, Que, Yok-Ai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388299/ https://www.ncbi.nlm.nih.gov/pubmed/28007922 http://dx.doi.org/10.1093/infdis/jiw632

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