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Diazoxide for Lowering Insulin Levels in Breast Cancer Patients
Diazoxide is a nondiuretic benzothiadiazine that produces hyperglycemia by lowering insulin levels through activation of ATP‐sensitive K1‐channels and stimulating insulin degradation in the lysosomal system. Its effect on cancer growth is discussed.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AlphaMed Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388385/ https://www.ncbi.nlm.nih.gov/pubmed/28400489 http://dx.doi.org/10.1634/theoncologist.2016-0402 |
| _version_ | 1782521120330612736 |
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| author | Fink, Michael K. Klement, Rainer J. |
| author_facet | Fink, Michael K. Klement, Rainer J. |
| author_sort | Fink, Michael K. |
| collection | PubMed |
| description | Diazoxide is a nondiuretic benzothiadiazine that produces hyperglycemia by lowering insulin levels through activation of ATP‐sensitive K1‐channels and stimulating insulin degradation in the lysosomal system. Its effect on cancer growth is discussed. |
| format | Online Article Text |
| id | pubmed-5388385 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | AlphaMed Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-53883852017-09-08 Diazoxide for Lowering Insulin Levels in Breast Cancer Patients Fink, Michael K. Klement, Rainer J. Oncologist Letters to the Editor Diazoxide is a nondiuretic benzothiadiazine that produces hyperglycemia by lowering insulin levels through activation of ATP‐sensitive K1‐channels and stimulating insulin degradation in the lysosomal system. Its effect on cancer growth is discussed. AlphaMed Press 2017-04 /pmc/articles/PMC5388385/ /pubmed/28400489 http://dx.doi.org/10.1634/theoncologist.2016-0402 Text en © AlphaMed Press 2017 |
| spellingShingle | Letters to the Editor Fink, Michael K. Klement, Rainer J. Diazoxide for Lowering Insulin Levels in Breast Cancer Patients |
| title | Diazoxide for Lowering Insulin Levels in Breast Cancer Patients |
| title_full | Diazoxide for Lowering Insulin Levels in Breast Cancer Patients |
| title_fullStr | Diazoxide for Lowering Insulin Levels in Breast Cancer Patients |
| title_full_unstemmed | Diazoxide for Lowering Insulin Levels in Breast Cancer Patients |
| title_short | Diazoxide for Lowering Insulin Levels in Breast Cancer Patients |
| title_sort | diazoxide for lowering insulin levels in breast cancer patients |
| topic | Letters to the Editor |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388385/ https://www.ncbi.nlm.nih.gov/pubmed/28400489 http://dx.doi.org/10.1634/theoncologist.2016-0402 |
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