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Novel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation

Both Mcm10 and HP1a are known to be required for DNA replication. However, underlying mechanism is not clarified yet especially for HP1. Knockdown of both HP1a and Mcm10 genes inhibited the progression of S phase in Drosophila eye imaginal discs. Proximity Ligation Assay (PLA) demonstrated that HP1a...

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Detalles Bibliográficos
Autores principales:	Vo, Nicole, Anh Suong, Dang Ngoc, Yoshino, Natsuki, Yoshida, Hideki, Cotterill, Sue, Yamaguchi, Masamitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388399/ https://www.ncbi.nlm.nih.gov/pubmed/28180289 http://dx.doi.org/10.1093/nar/gkw1174

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