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Disentangling polydispersity in the PCNA−p15(PAF) complex, a disordered, transient and multivalent macromolecular assembly

The intrinsically disordered p15(PAF) regulates DNA replication and repair when interacting with the Proliferating Cell Nuclear Antigen (PCNA) sliding clamp. As many interactions between disordered proteins and globular partners involved in signaling and regulation, the complex between p15(PAF) and...

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Detalles Bibliográficos
Autores principales: Cordeiro, Tiago N., Chen, Po-chia, De Biasio, Alfredo, Sibille, Nathalie, Blanco, Francisco J., Hub, Jochen S., Crehuet, Ramon, Bernadó, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388412/
https://www.ncbi.nlm.nih.gov/pubmed/28180305
http://dx.doi.org/10.1093/nar/gkw1183

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