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Disentangling polydispersity in the PCNA−p15(PAF) complex, a disordered, transient and multivalent macromolecular assembly
The intrinsically disordered p15(PAF) regulates DNA replication and repair when interacting with the Proliferating Cell Nuclear Antigen (PCNA) sliding clamp. As many interactions between disordered proteins and globular partners involved in signaling and regulation, the complex between p15(PAF) and...
Autores principales: | Cordeiro, Tiago N., Chen, Po-chia, De Biasio, Alfredo, Sibille, Nathalie, Blanco, Francisco J., Hub, Jochen S., Crehuet, Ramon, Bernadó, Pau |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388412/ https://www.ncbi.nlm.nih.gov/pubmed/28180305 http://dx.doi.org/10.1093/nar/gkw1183 |
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