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Salt-mediated two-site ligand binding by the cocaine-binding aptamer
Multisite ligand binding by proteins is commonly utilized in the regulation of biological systems and exploited in a range of biochemical technologies. Aptamers, although widely utilized in many rationally designed biochemical systems, are rarely capable of multisite ligand binding. The cocaine-bind...
Autores principales: | Neves, Miguel A.D., Slavkovic, Sladjana, Churcher, Zachary R., Johnson, Philip E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388413/ https://www.ncbi.nlm.nih.gov/pubmed/28025391 http://dx.doi.org/10.1093/nar/gkw1294 |
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