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Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding
RIG-I is an innate immune receptor that detects and responds to infection by deadly RNA viruses such as influenza, and Hepatitis C. In the cytoplasm, RIG-I is faced with a difficult challenge: it must sensitively detect viral RNA while ignoring the abundance of host RNA. It has been suggested that R...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388420/ https://www.ncbi.nlm.nih.gov/pubmed/28180316 http://dx.doi.org/10.1093/nar/gkw816 |