TEG-1 CD2BP2 controls miRNA levels by regulating miRISC stability in C. elegans and human cells

MiRNAs post-transcriptionally regulate gene expression by recruiting the miRNA-induced silencing complex (miRISC) to target mRNAs. However, the mechanisms by which miRISC components are maintained at appropriate levels for proper function are largely unknown. Here, we demonstrate that Caenorhabditis...

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Detalles Bibliográficos
Autores principales: Wang, Chris, Gupta, Pratyush, Fressigne, Lucile, Bossé, Gabriel D., Wang, Xin, Simard, Martin J., Hansen, Dave
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388422/
https://www.ncbi.nlm.nih.gov/pubmed/28180320
http://dx.doi.org/10.1093/nar/gkw836

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