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Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX)
LAGLIDADG homing endonucleases (LHEs) are a class of rare-cleaving nucleases that possess several unique attributes for genome engineering applications. An important approach for advancing LHE technology is the generation of a library of design ‘starting points’ through the discovery and characteriz...
Autores principales: | Jacoby, Kyle, Lambert, Abigail R., Scharenberg, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388424/ https://www.ncbi.nlm.nih.gov/pubmed/28180328 http://dx.doi.org/10.1093/nar/gkw864 |
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