A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)

Elucidating signaling pathways that regulate cellular metabolism is essential for a better understanding of normal development and tumorigenesis. Recent studies have shown that mitochondrial pyruvate carrier 1 (MPC1), a crucial player in pyruvate metabolism, is downregulated in colon adenocarcinomas...

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Detalles Bibliográficos
Autores principales: Sandoval, Imelda T, Delacruz, Richard Glenn C, Miller, Braden N, Hill, Shauna, Olson, Kristofor A, Gabriel, Ana E, Boyd, Kevin, Satterfield, Christeena, Van Remmen, Holly, Rutter, Jared, Jones, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388534/
https://www.ncbi.nlm.nih.gov/pubmed/28397687
http://dx.doi.org/10.7554/eLife.22706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388534/
https://www.ncbi.nlm.nih.gov/pubmed/28397687
http://dx.doi.org/10.7554/eLife.22706

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