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Comparative studies of vertebrate iduronate 2-sulfatase (IDS) genes and proteins: evolution of A mammalian X-linked gene
IDS is responsible for the lysosomal degradation of heparan sulfate and dermatan sulfate and linked to an X-linked lysosomal storage disease, mucopolysaccharidosis 2 (MPS2), resulting in neurological damage and early death. Comparative IDS amino acid sequences and structures and IDS gene locations w...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388652/ https://www.ncbi.nlm.nih.gov/pubmed/28401457 http://dx.doi.org/10.1007/s13205-016-0595-3 |