Exploring the Role of CYP3A4 Mediated Drug Metabolism in the Pharmacological Modulation of Nitric Oxide Production

Nitric-oxide synthase, the enzyme responsible for mammalian nitric oxide generation, and cytochrome P450, the major enzymes involved in drug metabolism, share striking similarities. Therefore, it makes sense that cytochrome P450 drug mediated biotransformations might play an important role in the ph...

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Detalles Bibliográficos
Autores principales: Pérez-del Palacio, José, Díaz, Caridad, Vergara, Noemí, Algieri, Francesca, Rodríguez-Nogales, Alba, de Pedro, Nuria, Rodríguez-Cabezas, M. Elena, Genilloud, Olga, Gálvez, Julio, Vicente, Francisca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388737/
https://www.ncbi.nlm.nih.gov/pubmed/28446877
http://dx.doi.org/10.3389/fphar.2017.00202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388737/
https://www.ncbi.nlm.nih.gov/pubmed/28446877
http://dx.doi.org/10.3389/fphar.2017.00202

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