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Plasmodium falciparum K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness In Vitro

The emergence and spread in Southeast Asia of Plasmodium falciparum resistance to artemisinin (ART) derivatives, the cornerstone of first-line artemisinin-based combination therapies (ACTs), underscore the urgent need to identify suitable replacement drugs. Discovery and development efforts have ide...

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Detalles Bibliográficos
Autores principales:	Straimer, Judith, Gnädig, Nina F., Stokes, Barbara H., Ehrenberger, Michelle, Crane, Audrey A., Fidock, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388803/ https://www.ncbi.nlm.nih.gov/pubmed/28400526 http://dx.doi.org/10.1128/mBio.00172-17

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