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Medial Ganglionic Eminence Progenitors Transplanted into Hippocampus Integrate in a Functional and Subtype-Appropriate Manner

Medial ganglionic eminence (MGE) transplantation rescues disease phenotypes in various preclinical models with interneuron deficiency or dysfunction, including epilepsy. While underlying mechanism(s) remains unclear to date, a simple explanation is that appropriate synaptic integration of MGE-derive...

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Detalles Bibliográficos
Autores principales: Hsieh, Jui-Yi, Baraban, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388838/
https://www.ncbi.nlm.nih.gov/pubmed/28413826
http://dx.doi.org/10.1523/ENEURO.0359-16.2017