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Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score)

Puberty is a key developmental event whose primary regulatory mechanisms remain poorly understood. Precise dating of puberty is crucial for experimental (preclinical) studies on its complex neuroendocrine controlling networks. In female laboratory rodents, external signs of puberty, such as vaginal...

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Detalles Bibliográficos
Autores principales: Gaytan, Francisco, Morales, Concepción, Leon, Silvia, Heras, Violeta, Barroso, Alexia, Avendaño, Maria S., Vazquez, Maria J., Castellano, Juan M., Roa, Juan, Tena-Sempere, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388887/
https://www.ncbi.nlm.nih.gov/pubmed/28401948
http://dx.doi.org/10.1038/srep46381