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Development and validation of a method for precise dating of female puberty in laboratory rodents: The puberty ovarian maturation score (Pub-Score)
Puberty is a key developmental event whose primary regulatory mechanisms remain poorly understood. Precise dating of puberty is crucial for experimental (preclinical) studies on its complex neuroendocrine controlling networks. In female laboratory rodents, external signs of puberty, such as vaginal...
Autores principales: | Gaytan, Francisco, Morales, Concepción, Leon, Silvia, Heras, Violeta, Barroso, Alexia, Avendaño, Maria S., Vazquez, Maria J., Castellano, Juan M., Roa, Juan, Tena-Sempere, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388887/ https://www.ncbi.nlm.nih.gov/pubmed/28401948 http://dx.doi.org/10.1038/srep46381 |
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