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Systems approach for the selection of micro-RNAs as therapeutic biomarkers of anti-EGFR monoclonal antibody treatment in colorectal cancer

miRNA plays an important role in tumourgenesis by regulating expression of oncogenes and tumour suppressors. Thus affects cell proliferation and differentiation, apoptosis, invasion and angiogenesis. miRNAs are potential biomarkers for diagnosis, prognosis and therapies of different forms of cancer....

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Detalles Bibliográficos
Autores principales: Deyati, Avisek, Bagewadi, Shweta, Senger, Philipp, Hofmann-Apitius, Martin, Novac, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389028/
https://www.ncbi.nlm.nih.gov/pubmed/25622824
http://dx.doi.org/10.1038/srep08013