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Systems approach for the selection of micro-RNAs as therapeutic biomarkers of anti-EGFR monoclonal antibody treatment in colorectal cancer
miRNA plays an important role in tumourgenesis by regulating expression of oncogenes and tumour suppressors. Thus affects cell proliferation and differentiation, apoptosis, invasion and angiogenesis. miRNAs are potential biomarkers for diagnosis, prognosis and therapies of different forms of cancer....
Autores principales: | Deyati, Avisek, Bagewadi, Shweta, Senger, Philipp, Hofmann-Apitius, Martin, Novac, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389028/ https://www.ncbi.nlm.nih.gov/pubmed/25622824 http://dx.doi.org/10.1038/srep08013 |
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