Cargando…

Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish

BACKGROUND: Exposure to environmental stressors during development may lead to latent and transgenerational adverse health effects. To understand the role of DNA methylation in these effects, we used zebrafish as a vertebrate model to investigate heritable changes in DNA methylation following chemic...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamstra, Jorke H., Sales, Liana Bastos, Aleström, Peter, Legler, Juliette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389146/
https://www.ncbi.nlm.nih.gov/pubmed/28413451
http://dx.doi.org/10.1186/s13072-017-0126-4