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Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish

BACKGROUND: Exposure to environmental stressors during development may lead to latent and transgenerational adverse health effects. To understand the role of DNA methylation in these effects, we used zebrafish as a vertebrate model to investigate heritable changes in DNA methylation following chemic...

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Detalles Bibliográficos
Autores principales:	Kamstra, Jorke H., Sales, Liana Bastos, Aleström, Peter, Legler, Juliette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389146/ https://www.ncbi.nlm.nih.gov/pubmed/28413451 http://dx.doi.org/10.1186/s13072-017-0126-4

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