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A case report of suspected malignant hyperthermia where patient survived the episode
Malignant hyperthermia is rare inherited disorder in our part of the world; there are only few cases reported in literature in India who were suspected of having this condition. The overall incidence of malignant hyperthermia during general anesthesia is estimated to range from 1: 5000 to 1: 50,000–...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389247/ https://www.ncbi.nlm.nih.gov/pubmed/28442967 http://dx.doi.org/10.4103/1658-354X.203057 |
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author | Iqbal, Asif Badoo, Shoaib Naqeeb, Ruqsana |
author_facet | Iqbal, Asif Badoo, Shoaib Naqeeb, Ruqsana |
author_sort | Iqbal, Asif |
collection | PubMed |
description | Malignant hyperthermia is rare inherited disorder in our part of the world; there are only few cases reported in literature in India who were suspected of having this condition. The overall incidence of malignant hyperthermia during general anesthesia is estimated to range from 1: 5000 to 1: 50,000–100,000 and mortality rate is estimated to be <5% in the presence of standard care. In India, there is no center where in vitro halothane caffeine contraction test is performed to confirm diagnosis in suspected cases. Second, dantrolene drug of choice for this condition is not freely available in market in India and is stored only in some hospitals in few major cities. Among the cases reported of suspected of malignant hyperthermia in India almost 50% have survived the condition despite nonavailability of dantrolene emphasizing role of early detection and aggressive management in these cases. |
format | Online Article Text |
id | pubmed-5389247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-53892472017-04-25 A case report of suspected malignant hyperthermia where patient survived the episode Iqbal, Asif Badoo, Shoaib Naqeeb, Ruqsana Saudi J Anaesth Case Report Malignant hyperthermia is rare inherited disorder in our part of the world; there are only few cases reported in literature in India who were suspected of having this condition. The overall incidence of malignant hyperthermia during general anesthesia is estimated to range from 1: 5000 to 1: 50,000–100,000 and mortality rate is estimated to be <5% in the presence of standard care. In India, there is no center where in vitro halothane caffeine contraction test is performed to confirm diagnosis in suspected cases. Second, dantrolene drug of choice for this condition is not freely available in market in India and is stored only in some hospitals in few major cities. Among the cases reported of suspected of malignant hyperthermia in India almost 50% have survived the condition despite nonavailability of dantrolene emphasizing role of early detection and aggressive management in these cases. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5389247/ /pubmed/28442967 http://dx.doi.org/10.4103/1658-354X.203057 Text en Copyright: © 2017 Saudi Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Iqbal, Asif Badoo, Shoaib Naqeeb, Ruqsana A case report of suspected malignant hyperthermia where patient survived the episode |
title | A case report of suspected malignant hyperthermia where patient survived the episode |
title_full | A case report of suspected malignant hyperthermia where patient survived the episode |
title_fullStr | A case report of suspected malignant hyperthermia where patient survived the episode |
title_full_unstemmed | A case report of suspected malignant hyperthermia where patient survived the episode |
title_short | A case report of suspected malignant hyperthermia where patient survived the episode |
title_sort | case report of suspected malignant hyperthermia where patient survived the episode |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389247/ https://www.ncbi.nlm.nih.gov/pubmed/28442967 http://dx.doi.org/10.4103/1658-354X.203057 |
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