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Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data
A new technique for shaping microfluid flow, known as flow sculpting, offers an unprecedented level of passive fluid flow control, with potential breakthrough applications in advancing manufacturing, biology, and chemistry research at the microscale. However, efficiently solving the inverse problem...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389406/ https://www.ncbi.nlm.nih.gov/pubmed/28402332 http://dx.doi.org/10.1038/srep46368 |
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author | Stoecklein, Daniel Lore, Kin Gwn Davies, Michael Sarkar, Soumik Ganapathysubramanian, Baskar |
author_facet | Stoecklein, Daniel Lore, Kin Gwn Davies, Michael Sarkar, Soumik Ganapathysubramanian, Baskar |
author_sort | Stoecklein, Daniel |
collection | PubMed |
description | A new technique for shaping microfluid flow, known as flow sculpting, offers an unprecedented level of passive fluid flow control, with potential breakthrough applications in advancing manufacturing, biology, and chemistry research at the microscale. However, efficiently solving the inverse problem of designing a flow sculpting device for a desired fluid flow shape remains a challenge. Current approaches struggle with the many-to-one design space, requiring substantial user interaction and the necessity of building intuition, all of which are time and resource intensive. Deep learning has emerged as an efficient function approximation technique for high-dimensional spaces, and presents a fast solution to the inverse problem, yet the science of its implementation in similarly defined problems remains largely unexplored. We propose that deep learning methods can completely outpace current approaches for scientific inverse problems while delivering comparable designs. To this end, we show how intelligent sampling of the design space inputs can make deep learning methods more competitive in accuracy, while illustrating their generalization capability to out-of-sample predictions. |
format | Online Article Text |
id | pubmed-5389406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-53894062017-04-14 Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data Stoecklein, Daniel Lore, Kin Gwn Davies, Michael Sarkar, Soumik Ganapathysubramanian, Baskar Sci Rep Article A new technique for shaping microfluid flow, known as flow sculpting, offers an unprecedented level of passive fluid flow control, with potential breakthrough applications in advancing manufacturing, biology, and chemistry research at the microscale. However, efficiently solving the inverse problem of designing a flow sculpting device for a desired fluid flow shape remains a challenge. Current approaches struggle with the many-to-one design space, requiring substantial user interaction and the necessity of building intuition, all of which are time and resource intensive. Deep learning has emerged as an efficient function approximation technique for high-dimensional spaces, and presents a fast solution to the inverse problem, yet the science of its implementation in similarly defined problems remains largely unexplored. We propose that deep learning methods can completely outpace current approaches for scientific inverse problems while delivering comparable designs. To this end, we show how intelligent sampling of the design space inputs can make deep learning methods more competitive in accuracy, while illustrating their generalization capability to out-of-sample predictions. Nature Publishing Group 2017-04-12 /pmc/articles/PMC5389406/ /pubmed/28402332 http://dx.doi.org/10.1038/srep46368 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Stoecklein, Daniel Lore, Kin Gwn Davies, Michael Sarkar, Soumik Ganapathysubramanian, Baskar Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data |
title | Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data |
title_full | Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data |
title_fullStr | Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data |
title_full_unstemmed | Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data |
title_short | Deep Learning for Flow Sculpting: Insights into Efficient Learning using Scientific Simulation Data |
title_sort | deep learning for flow sculpting: insights into efficient learning using scientific simulation data |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389406/ https://www.ncbi.nlm.nih.gov/pubmed/28402332 http://dx.doi.org/10.1038/srep46368 |
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