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Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm

The first binary cell fate decision occurs at the morula stage and gives rise to two distinct types of cells that constitute the trophectoderm (TE) and inner cell mass (ICM). The cell fate determinant, Cdx2, is induced in TE cells and plays an essential role in their differentiation and maintenance....

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Detalles Bibliográficos
Autores principales: Watanabe, Yusuke, Miyasaka, Kota Y., Kubo, Atsushi, Kida, Yasuyuki S., Nakagawa, Osamu, Hirate, Yoshikazu, Sasaki, Hiroshi, Ogura, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389439/
https://www.ncbi.nlm.nih.gov/pubmed/28401892
http://dx.doi.org/10.1038/srep46135