The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK

In vertebrates, the 7SK RNA forms the scaffold of a complex, which regulates transcription pausing of RNA-polymerase II. By binding to the HEXIM protein, the complex comprising proteins LARP7 and MePCE captures the positive transcription elongation factor P-TEFb and prevents phosphorylation of pausi...

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Detalles Bibliográficos
Autores principales: Martinez-Zapien, Denise, Legrand, Pierre, McEwen, Alastair G., Proux, Florence, Cragnolini, Tristan, Pasquali, Samuela, Dock-Bregeon, Anne-Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389472/
https://www.ncbi.nlm.nih.gov/pubmed/28082395
http://dx.doi.org/10.1093/nar/gkw1351

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