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And-1 is required for homologous recombination repair by regulating DNA end resection

Homologous recombination (HR) is a major mechanism to repair DNA double-strand breaks (DSBs). Although tumor suppressor CtIP is critical for DSB end resection, a key initial event of HR repair, the mechanism regulating the recruitment of CtIP to DSB sites remains largely unknown. Here, we show that...

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Detalles Bibliográficos
Autores principales: Li, Yongming, Li, Zongzhu, Wu, Ruiqin, Han, Zhiyong, Zhu, Wenge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389477/
https://www.ncbi.nlm.nih.gov/pubmed/27940557
http://dx.doi.org/10.1093/nar/gkw1241

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