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A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution

Since the discovery of oxidative demethylation of methylcytosine (mC) by Tet enzymes, an analytical method has been urgently needed that would enable the identification of mC and hydroxymethylcytosine (hmC) at the single base resolution level, because their roles in gene regulation are quite differe...

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Detalles Bibliográficos
Autores principales: Kawasaki, Yuki, Kuroda, Yukiko, Suetake, Isao, Tajima, Shoji, Ishino, Fumitoshi, Kohda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389479/
https://www.ncbi.nlm.nih.gov/pubmed/28204635
http://dx.doi.org/10.1093/nar/gkw994