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A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution
Since the discovery of oxidative demethylation of methylcytosine (mC) by Tet enzymes, an analytical method has been urgently needed that would enable the identification of mC and hydroxymethylcytosine (hmC) at the single base resolution level, because their roles in gene regulation are quite differe...
Autores principales: | Kawasaki, Yuki, Kuroda, Yukiko, Suetake, Isao, Tajima, Shoji, Ishino, Fumitoshi, Kohda, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389479/ https://www.ncbi.nlm.nih.gov/pubmed/28204635 http://dx.doi.org/10.1093/nar/gkw994 |
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