Cargando…
In vivo evidence that eIF3 stays bound to ribosomes elongating and terminating on short upstream ORFs to promote reinitiation
Translation reinitiation is a gene-specific translational control mechanism characterized by the ability of some short upstream ORFs to prevent recycling of the post-termination 40S subunit in order to resume scanning for reinitiation downstream. Its efficiency decreases with the increasing uORF len...
Autores principales: | Mohammad, Mahabub Pasha, Munzarová Pondělíčková, Vanda, Zeman, Jakub, Gunišová, Stanislava, Valášek, Leoš Shivaya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389480/ https://www.ncbi.nlm.nih.gov/pubmed/28119417 http://dx.doi.org/10.1093/nar/gkx049 |
Ejemplares similares
-
eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast
por: Mohammad, Mahabub Pasha, et al.
Publicado: (2021) -
Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs
por: Munzarová, Vanda, et al.
Publicado: (2011) -
In-depth analysis of cis-determinants that either promote or inhibit reinitiation on GCN4 mRNA after translation of its four short uORFs
por: Gunišová, Stanislava, et al.
Publicado: (2016) -
Please do not recycle! Translation reinitiation in microbes and higher eukaryotes
por: Gunišová, Stanislava, et al.
Publicado: (2017) -
Fail-safe mechanism of GCN4 translational control—uORF2 promotes reinitiation by analogous mechanism to uORF1 and thus secures its key role in GCN4 expression
por: Gunišová, Stanislava, et al.
Publicado: (2014)