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Allosteric regulation of helicase core activities of the DEAD-box helicase YxiN by RNA binding to its RNA recognition motif

DEAD-box proteins share a structurally similar core of two RecA-like domains (RecA_N and RecA_C) that contain the conserved motifs for ATP-dependent RNA unwinding. In many DEAD-box proteins the helicase core is flanked by ancillary domains. To understand the regulation of the DEAD-box helicase YxiN...

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Detalles Bibliográficos
Autores principales: Samatanga, Brighton, Andreou, Alexandra Z., Klostermeier, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389509/
https://www.ncbi.nlm.nih.gov/pubmed/28115633
http://dx.doi.org/10.1093/nar/gkx014