BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells

Bromodomain-containing protein 4 (BRD4) is a member of the bromo- and extraterminal (BET) domain-containing family of epigenetic readers which is under intensive investigation as a target for anti-tumor therapy. BRD4 plays a central role in promoting the expression of select subsets of genes includi...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagarajan, Sankari, Bedi, Upasana, Budida, Anusha, Hamdan, Feda H., Mishra, Vivek Kumar, Najafova, Zeynab, Xie, Wanhua, Alawi, Malik, Indenbirken, Daniela, Knapp, Stefan, Chiang, Cheng-Ming, Grundhoff, Adam, Kari, Vijayalakshmi, Scheel, Christina H., Wegwitz, Florian, Johnsen, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389510/
https://www.ncbi.nlm.nih.gov/pubmed/27980063
http://dx.doi.org/10.1093/nar/gkw1276

Ejemplares similares

Ejemplares similares