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Using predictive specificity to determine when gene set analysis is biologically meaningful

Gene set analysis, which translates gene lists into enriched functions, is among the most common bioinformatic methods. Yet few would advocate taking the results at face value. Not only is there no agreement on the algorithms themselves, there is no agreement on how to benchmark them. In this paper,...

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Detalles Bibliográficos
Autores principales: Ballouz, Sara, Pavlidis, Paul, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389513/
https://www.ncbi.nlm.nih.gov/pubmed/28204549
http://dx.doi.org/10.1093/nar/gkw957

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