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Using predictive specificity to determine when gene set analysis is biologically meaningful
Gene set analysis, which translates gene lists into enriched functions, is among the most common bioinformatic methods. Yet few would advocate taking the results at face value. Not only is there no agreement on the algorithms themselves, there is no agreement on how to benchmark them. In this paper,...
Autores principales: | Ballouz, Sara, Pavlidis, Paul, Gillis, Jesse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389513/ https://www.ncbi.nlm.nih.gov/pubmed/28204549 http://dx.doi.org/10.1093/nar/gkw957 |
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