TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a

The AT-rich interactive domain-containing protein 5a (Arid5a) plays a critical role in autoimmunity by regulating the half-life of Interleukin-6 (IL-6) mRNA. However, the signaling pathways underlying Arid5a-mediated regulation of IL-6 mRNA stability are largely uncharacterized. Here, we found that...

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Detalles Bibliográficos
Autores principales: Nyati, Kishan K., Masuda, Kazuya, Zaman, Mohammad Mahabub-Uz, Dubey, Praveen K., Millrine, David, Chalise, Jaya P., Higa, Mitsuru, Li, Songling, Standley, Daron M., Saito, Kazunobu, Hanieh, Hamza, Kishimoto, Tadamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389518/
https://www.ncbi.nlm.nih.gov/pubmed/28168301
http://dx.doi.org/10.1093/nar/gkx064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389518/
https://www.ncbi.nlm.nih.gov/pubmed/28168301
http://dx.doi.org/10.1093/nar/gkx064

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