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TLR4-induced NF-κB and MAPK signaling regulate the IL-6 mRNA stabilizing protein Arid5a
The AT-rich interactive domain-containing protein 5a (Arid5a) plays a critical role in autoimmunity by regulating the half-life of Interleukin-6 (IL-6) mRNA. However, the signaling pathways underlying Arid5a-mediated regulation of IL-6 mRNA stability are largely uncharacterized. Here, we found that...
Autores principales: | Nyati, Kishan K., Masuda, Kazuya, Zaman, Mohammad Mahabub-Uz, Dubey, Praveen K., Millrine, David, Chalise, Jaya P., Higa, Mitsuru, Li, Songling, Standley, Daron M., Saito, Kazunobu, Hanieh, Hamza, Kishimoto, Tadamitsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389518/ https://www.ncbi.nlm.nih.gov/pubmed/28168301 http://dx.doi.org/10.1093/nar/gkx064 |
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